SHU 9119

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The efficacy and specificity of SHU-9119 as an MC3/MC4 receptor antagonist in the rat was first validated in vitro and in vivo. In vitro, in heterologous cells expressing either rat MC3-R or MC4-R, the major MCR subtypes expressed in brain, SHU-9119 showed no intrinsic agonism.

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Sequence (One-Letter Code):

Ac-Nle-cyclo{DH-dNal(2′)-RWK}-NH2

 

Sequence (Three-Letter Code):

Ac-Nle-cyclo({Asp}{His}{dNal(2′)}{Arg}{Trp}{Lys})-NH2

 

Molecular Weight:

1074.2

 

Purity:
% Peak Area By HPLC ≥ 95%

 

Salt:
TFA Salt

 

Storage:

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

 

Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

 

Documents:

MSDS

Amount

0.5 mg, 1 mg, Other