Orexin B, rat, mouse

$90.00$155.00

Orexin B is a hypothalamatic neuropeptide stimulating food intake in rats. Orexin B activates OX2 receptors. Both OX1 and OX2 receptors are involved in maintaining arousal. OX2 receptors appear to be inhibitory autoreceptors on orexin-containing neurons. Orexin B stimulates food consumption in a similar manner to orexin A, but the effect did not last as long as that of orexin A. The affinity of orexin B for the OX1 receptor is significantly lower than that of orexin A. Binding affinities for the OX2 receptor are similar for orexin A and B.

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Sequence (One-Letter Code):

RPGPPGLQGRLQRLLQANGNHAAGILTM-NH2

 

Sequence (Three-Letter Code):

{Arg}{Pro}{Gly}{Pro}{Pro}{Gly}{Leu}{Gln}{Gly}{Arg}{Leu}{Gln}{Arg}{Leu}{Leu}{Gln}{Ala}{Asn}{Gly}{Asn}{His}{Ala}{Ala}{Gly}{Ile}{Leu}{Thr}{Met}-NH2

 

Molecular Weight:

2936.4

 

Purity:
% Peak Area By HPLC ≥ 95%

 

Salt:
TFA Salt

 

Storage:

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

 

Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

 

Documents:

MSDS

Amount

0.5 mg, 1 mg, Other