[Leu5]-Enkephalin

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[Leu5]-enkephalin is an opioid peptide that has been found to modulate nociception in the spinal cord. This opiate peptide functions as a modulator of neurotransmission. [Leu5]-enkephalin induces circular muscle contractions and reduces immunoreactive vasoactive intestinal peptide secretion. Some anatomical results suggest that neurons containing immunoreactive [Leu5]-enkephalin in the dorsal horn, some of which may receive input from primary afferents, modulate nociception by directly synapsing with cells of origin of the spinothalamic tract and also by interacting with primary afferent terminals.

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Catolog No: N/A Category:

Sequence (One-Letter Code):

YGGFL

 

Sequence (Three-Letter Code):

{Tyr}{Gly}{Gly}{Phe}{Leu}

 

Molecular Weight:

555.6

 

Purity:
% Peak Area By HPLC ≥ 95%

 

Salt:
TFA Salt

 

Storage:

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

 

Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

 

Documents:

MSDS

Amount

5 mg, 10 mg, Other