IRBP (1-20), human

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This peptide is a 1 to 20 amino acid fragment of the interphotoreceptor retinoid binding protein (IRBP). IRBP is a 140-kDa glycolipoprotein residing in the interphotoreceptor matrix between the neural retina and the retinal pigment epithelium. Human IRBP peptide 1-20 contains a major epitope for the H-2b haplotype. Immunization with IRBP (1 – 20) induces T-cell–mediated experimental autoimmune uveoretinitis (EAU) disease. The pathology of disease induced by the peptide, or by adoptive transfer of cells specific to the peptide, is similar to that induced by the whole IRBP protein.

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Catolog No: N/A Category:

Sequence (One-Letter Code):

GPTHLFQPSLVLDMAKVLLD

 

Sequence (Three-Letter Code):

{Gly}{Pro}{Thr}{His}{Leu}{Phe}{Gln}{Pro}{Ser}{Leu}{Val}{Leu}{Asp}{Met}{Ala}{Lys}{Val}{Leu}{Leu}{Asp}

 

Molecular Weight:

2194.6

 

Purity:
% Peak Area By HPLC ≥ 95%

 

Salt:
TFA Salt

 

Storage:

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

 

Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

 

Documents:

MSDS

Amount

1 mg, 5 mg, Other