Handle region peptide (HRP), rat

$45.00$100.00

A decoy receptor, or sink receptor, is a receptor that binds a ligand, inhibiting it from binding to its normal receptor. For instance, the receptor VEGFR-1 can prevent vascular endothelial growth factor (VEGF) from binding to the VEGFR-2.When a prorenin-binding protein interacts with the “handle” region of the prorenin prosegment, the prorenin molecule undergoes a conformational change to an enzymatically active state (5). This phenomenon is called nonproteolytic activation.

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Sequence (One-Letter Code):

RILLKKMPSV

 

Sequence (Three-Letter Code):

{Arg}{Ile}{Leu}{Leu}{Lys}{Lys}{Met}{Pro}{Ser}{Val}

 

Molecular Weight:

1184.5

 

Purity:
% Peak Area By HPLC ≥ 95%

 

Salt:
TFA Salt

 

Storage:

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

 

Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

 

Documents:

MSDS

Amount

1 mg, 5 mg, Other