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Endomorphin 2 is a potent, selective endogenous µ opioid receptor agonist. The physiological function of endomorphin-2 as a neurotransmitter or neuromodulator may cease through the rapid enzymatic process in the synapse of brain, as for other neuropeptides. Some results indicate that the administration of the endogenous µ-opioid ligand endomorphin-2, but not endomorphin-1, into the brain produces an antitussive effect via mainly naloxonazine-insensitive µ-opioid receptors, namely µ2-opioid receptors and partially kappa-opioid receptors.
Sequence (One-Letter Code):
YPFF-NH2
Sequence (Three-Letter Code):
{Tyr}{Pro}{Phe}{Phe}-NH2
Molecular Weight:
571.7
Purity:
% Peak Area By HPLC ≥ 95%
Salt:
TFA Salt
Storage:
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Documents:
| Amount | 5 mg, 10 mg, Other |
|---|
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