Colivelin

$153.00$455.00

Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN). Colivelin is constructed as activity-dependent neurotrophic factor (ADNF) C-terminally fused to AGA-(C8R) HNG17, which is a potent HN derivative. Cell death induced by overexpressed familial Alzheimer’s disease (FAD)-causative genes and beta-amyloid (1-43) can be completely suppressed by colivelin. Colivelin administered intraperitoneally suppresses memory impairment and may serve as a novel drug candidate to treat Alzheimer’s disease.

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Catolog No: N/A Category:

Sequence (One-Letter Code):

SALLRSIPAPAGASRLLLLTGEIDLP

 

Sequence (Three-Letter Code):

{Ser}{Ala}{Leu}{Leu}{Arg}{Ser}{Ile}{Pro}{Ala}{Pro}{Ala}{Gly}{Ala}{Ser}{Arg}{Leu}{Leu}{Leu}{Leu}{Thr}{Gly}{Glu}{Ile}{Asp}{Leu}{Pro}

 

Molecular Weight:

2645.1

 

Purity:
% Peak Area By HPLC ≥ 95%

 

Salt:
TFA Salt

 

Storage:

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

 

Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

 

Documents:

MSDS

Amount

1 mg, 5 mg, Other