$24.00 – $75.00
The bradykinin (BK) fragment (1-5) (RPPGF) is among the most stable of naturally occurring metabolites. Bradykinin (1-5) may be used as a marker for BK production in vivo. It is known that an intact Arg residue in the C-terminus is required for certain biological activities. BK 1-5 is the smallest peptide that can inhibit _-thrombin-induced platelet aggregation and secretion and calcium mobilization. Bradykinin (1-5) also prevents _-thrombin from cleaving the thrombin receptor peptide, NATLDPRSFLLR, between arginine and serine. Such antithrombin activities of BK 1-5 may contribute to the cardioprotective nature of kinins.
Sequence (One-Letter Code):
RPPGF
Sequence (Three-Letter Code):
{Arg}{Pro}{Pro}{Gly}{Phe}
Molecular Weight:
572.7
Purity:
% Peak Area By HPLC ≥ 95%
Salt:
TFA Salt
Storage:
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Documents:
| Amount | 1 mg, 5 mg, Other |
|---|
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