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Films formed from 1,12-diphosphonododecane were treated with zirconium tetra (tert-butoxide) to give surface Zr complex species; derivatives of these surface complexes are stable to hydrolysis under physiological conditions and are mechanically strong. The cell attractive peptide derivative ARG-GLY-ASP-CYS, RGDC can be bound to these surface Zr alkoxide complexes through (maleimido) alkylcarboxylate intermediates. Surfaces modified with RGDC were shown to be effective for osteoblast binding and proliferation.
Sequence (One-Letter Code):
RGDC
Sequence (Three-Letter Code):
{Arg}{Gly}{Asp}{Cys}
Molecular Weight:
449.5
Purity:
% Peak Area By HPLC ≥ 95%
Salt:
TFA Salt
Storage:
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Documents:
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