43Gap 26, Connexin Mimetic

$42.00$140.00

This Gap 26 peptide is derived from the first extracellular loop sequence of connexin (Cx) 43. This short mimetic peptide reversibly inhibits the gap junction-dependent propagation of Ca2+ waves between tracheal airway epithelial cells. Connexins, or gap junctions, are a family of structurally-related transmembrane proteins. Gap junctions contain channels that allow the passage of ions and small molecules between adjacent cells molecules. Calcium and inositol phosphates are among the second messengers that can pass through gap junction channels.

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Catolog No: N/A Category:

Sequence (One-Letter Code):

VCYDKSFPISHVR

 

Sequence (Three-Letter Code):

{Val}{Cys}{Tyr}{Asp}{Lys}{Ser}{Phe}{Pro}{Ile}{Ser}{His}{Val}{Arg}

 

Molecular Weight:

1549.8

 

Purity:
% Peak Area By HPLC ≥ 95%

 

Salt:
TFA Salt

 

Storage:

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

 

Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

 

Documents:

MSDS

Amount

1 mg, 5 mg, Other