Mast Cell Degranulating Peptide

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Mast Cell Degranulating Peptide (MCDP) is a neurotoxic agent isolated from bee venom. It produces a long-term potentiation in the hippocampus. Some studies show that Mast Cell Degranulating Peptide (MCDP) augments the release of excitatory and inhibitory transmitter by an action, which is independent of calcium influx, through voltage-dependent channels. Mast Cell Degranulating Peptide (MCDP) inhibited non-competitively the binding of both radiolabelled dendrotoxin and beta-bungarotoxin but with relatively low potency.

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Sequence (One-Letter Code):

IKCNCKRHVIKPHICRKICGKN-NH2

 

Sequence (Three-Letter Code):

{Ile}{Lys}{Cys}{Asn}{Cys}{Lys}{Arg}{His}{Val}{Ile}{Lys}{Pro}{His}{Ile}{Cys}{Arg}{Lys}{Ile}{Cys}{Gly}{Lys}{Asn}-NH2

 

Molecular Weight:

2587.2

 

Purity:
% Peak Area By HPLC ≥ 95%

 

Salt:
TFA Salt

 

Storage:

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

 

Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

 

Documents:

MSDS

Amount

0.5 mg, 1 mg, Other