Annexin 1 (ANXA-1, Ac 2-26)

$180.00$655.00

This acetylated peptide is amino acids 2 to 28 N-terminus fragment of Annexin 1 (ANXA1). ANXA1, previously referred to as lipocortin 1 or LC1, is a member of the annexin superfamily that has potent leukocyte antimigratory activity. This fragment, as well as the full-length ANXA1, may significantly reduce polymorphonuclear leukocyte (PMN) influx in mice. ANXA1 and ANXA1 mimetics, such as Ac (2-12), inhibit recruitment of neutrophils in acute and chronic inflammation. This peptide is able to inhibit neutrophil extravasation.

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Sequence (One-Letter Code):

Ac-AMVSEFLKQAWIENEEQEYVVQTVK

 

Sequence (Three-Letter Code):

Ac-{Ala}{Met}{Val}{Ser}{Glu}{Phe}{Leu}{Lys}{Gln}{Ala}{Trp}{Ile}{Glu}{Asn}{Glu}{Glu}{Gln}{Glu}{Tyr}{Val}{Val}{Gln}{Thr}{Val}{Lys}

 

Molecular Weight:

3041.4

 

Purity:
% Peak Area By HPLC ≥ 95%

 

Salt:
TFA Salt

 

Storage:

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

 

Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

 

Documents:

MSDS

Amount

1 mg, 5 mg, Other