beta-Amyloid (1-16)
Proteins interactions with reactive oxygen agents may result in covalent modifications of amino acid residues in proteins, formation of protein-protein cross-linkages and oxidation of the protein backbone resulting in protein fragmentation. Oxidation targets for Beta-amyloid (1-16) are the histidine residues coordinated to the metal ions. Copper is bound to Aß in senile plaque of Alzheimer's disease with Beta-amyloid (1-16) taking part in the coordination of the Cu2+ ions. Cu2+ and Zn2+ are linked with the neurotoxicity of Aß and free radical damage.
Amount:
Catalog No.: N/A
Category: beta-Amyloid
Sequence (One-Letter Code):
DAEFRHDSGYEVHHQK
Sequence (Three-Letter Code):
{Asp}{Ala}{Glu}{Phe}{Arg}{His}{Asp}{Ser}{Gly}{Tyr}{Glu}{Val}{His}{His}{Gln}{Lys}
Molecular Weight:
1955
Purity:
% Peak Area By HPLC ≥ 95%
Salt:
TFA Salt
Storage:
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.