Handle region peptide (HRP), rat
A decoy receptor, or sink receptor, is a receptor that binds a ligand, inhibiting it from binding to its normal receptor. For instance, the receptor VEGFR-1 can prevent vascular endothelial growth factor (VEGF) from binding to the VEGFR-2.When a prorenin-binding protein interacts with the “handle” region of the prorenin prosegment, the prorenin molecule undergoes a conformational change to an enzymatically active state (5). This phenomenon is called nonproteolytic activation.
Amount:
Catalog No.: N/A
Category: Angiotensins and Related Peptides
Sequence (One-Letter Code):
RILLKKMPSV
Sequence (Three-Letter Code):
{Arg}{Ile}{Leu}{Leu}{Lys}{Lys}{Met}{Pro}{Ser}{Val}
Molecular Weight:
1184.5
Purity:
% Peak Area By HPLC ≥ 95%
Salt:
TFA Salt
Storage:
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.